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Citicoline Dosage

Daily Dose of Citicoline: 500-2000mg

Supplementing with Citicoline

Citicoline increases neurotransmitter activity. Photo Credit: https://www.flickr.com/photos/billselak/

Citicoline is a brain supplement, or nootropic, that is considered to be one of the most effective and powerful available in the market. It is a nutrient that is already naturally occurring in the body and is a water soluble compound. It is necessary in the structure of phosphatidylcholine, which is a major component of grey matter brain tissue. Citicoline was developed in Japan for people who had suffered a specific type of stroke, so that they could recover better. Studies have shown that it can help people who are suffering from glaucoma. It is capable of nourishing nerves as well as improving blood circulation within the brain, making it a very powerful nootropic.

One of its major benefits is that Citicoline increases the level of the neurotransmitter Acetylcholine in the brain. Neurotransmitters communicate between your neurons, which have a vital role in the development and formation of cognitive processes. Many reports have claimed that when taking citicoline supplements, there have been improvements in memory recall speed, enhanced brain metabolism, improved blood circulation in the brain, increased attention span, focus, and concentration, as well as greater amounts of motivation and vitality. Clinical uses and benefits of citicoline include treatment for cerebral vascular disease, head trauma, and a number of different cognitive disorders including dementia and age related cognitive decline. It works because citicoline is a source of choline, which is a nutrient similar to the B Vitamins that are necessary for the brain to be able to make the acetylcholine neurotransmitter. Many people can’t get enough choline from their diet which can lead to mental impairment even with minor deficiencies. Supplements can help increase the amount of choline in the bloodstream to promote greater acetylcholine production, which then increases brainpower.

A few and generally very mild side effects of citicoline have been reported and include headaches, diarrhea, nausea, insomnia, and other intestinal issues. Most people who take the recommended dose of 500-2,000mg a day should have no trouble. For optimum results, it can be taken with other nootropic supplements like the ones you’ll find in the racetam family because it can potentiate their effectiveness as well as reduce side effects.




  • Bruce SE1, Werner KB, Preston BF, Baker LM. Improvements in concentration, working memory and sustained attention following consumption of a natural citicoline-caffeine beverage. Int J Food Sci Nutr. 2014 Jul 21:1-5. PMID: 25046515.
  • Roberti G1, Tanga L, Parisi V, Sampalmieri M, Centofanti M, Manni G. A preliminary study of the neuroprotective role of citicoline eye drops in glaucomatous optic neuropathy. Indian J Ophthalmol. 2014 May;62(5):549-53. PMID: 24881599.

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