Forskolin Dosage

Daily Dose of Forskolin: 250mg of 10% extract

Photo Credit: http://www.flickr.com/photos/phuonglovejesus2782010/

Photo Credit: http://www.flickr.com/photos/phuonglovejesus2782010/

Forskolin is extracted from the plant Coleus forskohli and has been used in traditional Ayurvedic medicine. Traditionally, it was used for a variety of diseases and conditions like asthma, eczema, hypertension, digestive disorders, and other conditions like neck stiffness and as an oral contraceptive. It was also used to treat heart, blood, and circulatory conditions. These days, Forskolin is used to treat a heart condition called idiopathic congestive cardiomyopathy. To treat this condition, it is given intravenously by a healthcare provider. It works by stimulating the muscles in the heart and in the walls of the blood vessels. This leads to producing more powerful heartbeats and the widening of blood vessels. Forskolin is also possibly effective in treating asthma when it is inhaled. However, these claims are still being tested in the preliminary stage and more studies need to be conducted to prove its effectiveness and safety.

A study was done with overweight men who were given Forskolin and the results were a decrease in body fat and an increase in bone mass. They took the supplement twice a day in a period of 12 weeks. However, when a study was done with overweight women, there were no weight loss benefits but it did help to prevent further weight gain. The recommended dosage for treating obesity is 250mg of a 10% extract twice a day for 12 weeks. For asthma, it is 10mg daily for 206 months. Forskolin has some dangerous side effects so it is important to talk to your doctor before taking it. Some of its side effects include hypotension, increase heart rate, and increased stomach acid levels. Hypotension can cause dizziness, nausea and fatigue. Low blood pressure levels can prevent vital organs from getting adequate oxygen. An increased heart rate can be dangerous because it can lead to heart failure, blood clots, and even sudden death. An increase of stomach acid levels can be dangerous for those who are already experiencing gastrointestinal problems.

Sources:
http://www.drugs.com/npc/forskolin.html
http://www.naturodoc.com/forskolin.htm
http://www.livestrong.com/article/517641-forskolin-and-weight-loss/

References

  • Godard MP1, Johnson BA, Richmond SR. Body composition and hormonal adaptations associated with forskolin consumption in overweight and obese men. Obes Res. 2005 Aug;13(8):1335-43. PMID: 16129715.
  • Tamma G1, Ranieri M, Dossena S, Di Mise A, Nofziger C, Svelto M, Paulmichl M, Valenti G. A FRET-based approach for quantitative evaluation of forskolin-induced pendrin trafficking at the plasma membrane in bronchial NCI H292 cells. Cell Physiol Biochem. 2013;32(7):200-9. PMID: 24429826.
  • Wang Q1, Fong R, Mason P, Fox AP, Xie Z. Caffeine Accelerates Recovery from General Anesthesia. J Neurophysiol. 2013 Dec 26. PMID: 24375022.

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